Bath Rugby flanker Francois Louw and wing Horacio Agulla will both be in international action this weekend in the Rugby Championship.
Louw is named in the starting line-up for the Springboks, who have dropped Morne Steyn at fly-half in favour of Johan Goosen. It will be Goosen's first start as he comes into the side to take on Australia at Loftus Versfeld in Pretoria on Saturday.
Springbok coach Heyneke Meyer said the Springboks were looking forward to Saturday's Test and realised the importance of the match.
"It's great to be back home in South Africa after three tough matches on the road. We were not happy with the results in Mendoza, Perth or Dunedin and we know how big the Test at Loftus Versfeld is on Saturday," said Meyer.